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Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface

Nitrosylation of sulfhydryl (SH) groups of cysteine (Cys) moieties is an important post-translational modification (PTM), often on a par with phosphorylation. S-Nitrosoalbumin (ALB-Cys(34)SNO; SNALB) in plasma and S-nitrosohemoglobin (Hb-Cys(β93)SNO; HbSNO) in red blood cells are considered the most...

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Detalles Bibliográficos
Autor principal: Tsikas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107154/
https://www.ncbi.nlm.nih.gov/pubmed/33586042
http://dx.doi.org/10.1007/s00726-021-02950-8