Surgery Performed Under Propofol Anesthesia Induces Cognitive Impairment and Amyloid Pathology in ApoE4 Knock-In Mouse Model

Background: Postoperative cognitive dysfunction (POCD) following anesthesia and surgery is a common and severe complication, especially in elderly patients. A pre-existing cognitive impairment may impart susceptibility to further cognitive dysfunction; the mechanism remains unclear. We hypothesized...

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Detalles Bibliográficos
Autores principales: Kim, Jong-Ho, Jung, Harry, Lee, Yeonkyeong, Sohn, Jong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107235/
https://www.ncbi.nlm.nih.gov/pubmed/33981208
http://dx.doi.org/10.3389/fnagi.2021.658860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107235/
https://www.ncbi.nlm.nih.gov/pubmed/33981208
http://dx.doi.org/10.3389/fnagi.2021.658860

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