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Optimization of T Cell Redirecting Strategies: Obtaining Inspirations From Natural Process of T Cell Activation

Chimeric antigen receptors (CARs) or bispecific antibodies (bsAbs) redirected T cell against tumors is one of the most promising immunotherapy approaches. However, insufficient clinical outcomes are still observed in treatments of both solid and non-solid tumors. Limited efficacy and poor persistenc...

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Detalles Bibliográficos
Autores principales: Gao, Yiyuan, Wang, Yuedi, Luo, Feifei, Chu, Yiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107274/
https://www.ncbi.nlm.nih.gov/pubmed/33981310
http://dx.doi.org/10.3389/fimmu.2021.664329