Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1

PURPOSE: The trimethylation of histone H3 at lysine 4 (H3K4me3) facilitates transcriptional gene activation, and Setd1a is the methyltransferase specific to H3K4. H3K4me3 has been reported to regulate rod photoreceptor differentiation; however, the roles H3K4me3 plays in retinal progenitor cell (RPC...

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Detalles Bibliográficos
Autores principales: Deng, Xiaoyue, Iwagawa, Toshiro, Fukushima, Masaya, Suzuki, Yutaka, Watanabe, Sumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107498/
https://www.ncbi.nlm.nih.gov/pubmed/33938913
http://dx.doi.org/10.1167/iovs.62.6.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107498/
https://www.ncbi.nlm.nih.gov/pubmed/33938913
http://dx.doi.org/10.1167/iovs.62.6.1

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