Distinct patterns of somatic genomic alterations and mutational signatures in central and peripheral-type small-cell lung cancer

BACKGROUND: Generally, small-cell lung cancer (SCLC) can be classified into central and peripheral-type. Genomic landscape and genetic heterogeneity between central and peripheral-type SCLCs is scarce. METHODS: We conducted whole-exome sequencing (WES) of 41 tumor/control pairs of SCLC samples. In a...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Wang, Jing, Hu, Juanni, Song, Lele, Ni, Jian, He, Yayi, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107737/
https://www.ncbi.nlm.nih.gov/pubmed/34012790
http://dx.doi.org/10.21037/tlcr-20-1096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107737/
https://www.ncbi.nlm.nih.gov/pubmed/34012790
http://dx.doi.org/10.21037/tlcr-20-1096

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