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Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma

BACKGROUND: Targeted genetic profiling of tissue samples is paramount to detect druggable genetic aberrations in patients with non-squamous non-small cell lung cancer (NSCLC). Accurate upfront estimation of tumor cell content (TCC) is a crucial pre-analytical step for reliable testing and to avoid f...

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Detalles Bibliográficos
Autores principales: Kazdal, Daniel, Rempel, Eugen, Oliveira, Cristiano, Allgäuer, Michael, Harms, Alexander, Singer, Kerstin, Kohlwes, Elke, Ormanns, Steffen, Fink, Ludger, Kriegsmann, Jörg, Leichsenring, Michael, Kriegsmann, Katharina, Stögbauer, Fabian, Tavernar, Luca, Leichsenring, Jonas, Volckmar, Anna-Lena, Longuespée, Rémi, Winter, Hauke, Eichhorn, Martin, Heußel, Claus Peter, Herth, Felix, Christopoulos, Petros, Reck, Martin, Muley, Thomas, Weichert, Wilko, Budczies, Jan, Thomas, Michael, Peters, Solange, Warth, Arne, Schirmacher, Peter, Stenzinger, Albrecht, Kriegsmann, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107748/
https://www.ncbi.nlm.nih.gov/pubmed/34012783
http://dx.doi.org/10.21037/tlcr-20-1168