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Cytotoxic Effect of Progesterone, Tamoxifen and Their Combination in Experimental Cell Models of Human Adrenocortical Cancer

Progesterone (Pg) and estrogen (E) receptors (PgRs and ERs) are expressed in normal and neoplastic adrenal cortex, but their role is not fully understood. In literature, Pg demonstrated cytotoxic activity on AdrenoCortical Carcinoma (ACC) cells, while tamoxifen is cytotoxic in NCI-H295R cells. Here,...

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Detalles Bibliográficos
Autores principales: Rossini, Elisa, Tamburello, Mariangela, Abate, Andrea, Beretta, Silvia, Fragni, Martina, Cominelli, Manuela, Cosentini, Deborah, Hantel, Constanze, Bono, Federica, Grisanti, Salvatore, Poliani, Pietro Luigi, Tiberio, Guido A. M., Memo, Maurizio, Sigala, Sandra, Berruti, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108132/
https://www.ncbi.nlm.nih.gov/pubmed/33981288
http://dx.doi.org/10.3389/fendo.2021.669426