Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy

BACKGROUND: Biglycan is a proteoglycan found in the extracellular matrix. We have previously shown that biglycan is secreted from tumor endothelial cells and induces tumor angiogenesis and metastasis. However, the function of stroma biglycan in breast cancer is still unclear. METHODS: Biglycan gene...

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Detalles Bibliográficos
Autores principales: Cong, Li, Maishi, Nako, Annan, Dorcas A., Young, Marian F., Morimoto, Hirofumi, Morimoto, Masahiro, Nam, Jin-Min, Hida, Yasuhiro, Hida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108358/
https://www.ncbi.nlm.nih.gov/pubmed/33966638
http://dx.doi.org/10.1186/s13058-021-01423-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108358/
https://www.ncbi.nlm.nih.gov/pubmed/33966638
http://dx.doi.org/10.1186/s13058-021-01423-w

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