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Strategies for Bacteriophage T5 Mutagenesis: Expanding the Toolbox for Phage Genome Engineering

Phage genome editing is crucial to uncover the molecular mechanisms of virus infection and to engineer bacteriophages with enhanced antibacterial properties. Phage genetic engineering relies mostly on homologous recombination (HR) assisted by the targeted elimination of wild-type phages by CRISPR-Ca...

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Detalles Bibliográficos
Autores principales: Ramirez-Chamorro, Luis, Boulanger, Pascale, Rossier, Ombeline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108384/
https://www.ncbi.nlm.nih.gov/pubmed/33981295
http://dx.doi.org/10.3389/fmicb.2021.667332