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Endogenous retroviruses in the origins and treatment of cancer

Endogenous retroviruses (ERVs) are emerging as promising therapeutic targets in cancer. As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate expression from gene networks, including those underpinning embryogenesis and immune cell function. ERV activation can prom...

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Detalles Bibliográficos
Autores principales: Jansz, Natasha, Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108463/
https://www.ncbi.nlm.nih.gov/pubmed/33971937
http://dx.doi.org/10.1186/s13059-021-02357-4