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Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis

BACKGROUND: Gram-negative bacterial infections have a major economic impact on both the livestock industry and public health. Toll-like receptor 4 (TLR4) plays a crucial role in host defence against Gram-negative bacteria. Exploring the defence mechanism regulated by TLR4 may provide new targets for...

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Detalles Bibliográficos
Autores principales: Li, Yao, Zhao, Yue, Xu, Xueling, Zhang, Rui, Zhang, Jinlong, Zhang, Xiaosheng, Li, Yan, Deng, Shoulong, Lian, Zhengxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108469/
https://www.ncbi.nlm.nih.gov/pubmed/33966642
http://dx.doi.org/10.1186/s40104-021-00585-z