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Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis
BACKGROUND: Gram-negative bacterial infections have a major economic impact on both the livestock industry and public health. Toll-like receptor 4 (TLR4) plays a crucial role in host defence against Gram-negative bacteria. Exploring the defence mechanism regulated by TLR4 may provide new targets for...
Autores principales: | Li, Yao, Zhao, Yue, Xu, Xueling, Zhang, Rui, Zhang, Jinlong, Zhang, Xiaosheng, Li, Yan, Deng, Shoulong, Lian, Zhengxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108469/ https://www.ncbi.nlm.nih.gov/pubmed/33966642 http://dx.doi.org/10.1186/s40104-021-00585-z |
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