Cargando…

The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80

Par1b/MARK2 is a Ser/Thr kinase with pleiotropic effects that participates in the generation of apico-basal polarity in Caenorhabditis elegans. It is phosphorylated by atypical PKC(ι/λ) in Thr595 and inhibited. Because previous work showed a decrease in atypical protein kinase C (aPKC) activity unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashukova, Anastasia, Forteza, Radia, Shah, Viraj N., Salas, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108508/
https://www.ncbi.nlm.nih.gov/pubmed/33596087
http://dx.doi.org/10.1091/mbc.E20-10-0646