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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone

A range of severe human diseases called ciliopathies is caused by the dysfunction of primary cilia. Primary cilia are cytoplasmic protrusions consisting of the basal body (BB), the axoneme, and the transition zone (TZ). The BB is a modified mother centriole from which the axoneme, the microtubule-ba...

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Detalles Bibliográficos
Autores principales: Wiegering, Antonia, Dildrop, Renate, Vesque, Christine, Khanna, Hemant, Schneider-Maunoury, Sylvie, Gerhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108517/
https://www.ncbi.nlm.nih.gov/pubmed/33625872
http://dx.doi.org/10.1091/mbc.E20-03-0190