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Rpgrip1l controls ciliary gating by ensuring the proper amount of Cep290 at the vertebrate transition zone
A range of severe human diseases called ciliopathies is caused by the dysfunction of primary cilia. Primary cilia are cytoplasmic protrusions consisting of the basal body (BB), the axoneme, and the transition zone (TZ). The BB is a modified mother centriole from which the axoneme, the microtubule-ba...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108517/ https://www.ncbi.nlm.nih.gov/pubmed/33625872 http://dx.doi.org/10.1091/mbc.E20-03-0190 |