Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2

The role of desmosomal cadherin desmocollin-2 (Dsc2) in regulating barrier function in intestinal epithelial cells (IECs) is not well understood. Here, we report the consequences of silencing Dsc2 on IEC barrier function in vivo using mice with inducible intestinal–epithelial-specific Dsc2 knockdown...

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Detalles Bibliográficos
Autores principales: Raya-Sandino, Arturo, Luissint, Anny-Claude, Kusters, Dennis H. M., Narayanan, Vani, Flemming, Sven, Garcia-Hernandez, Vicky, Godsel, Lisa M., Green, Kathleen J., Hagen, Susan J., Conway, Daniel E., Parkos, Charles A., Nusrat, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108520/
https://www.ncbi.nlm.nih.gov/pubmed/33596089
http://dx.doi.org/10.1091/mbc.E20-12-0775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108520/
https://www.ncbi.nlm.nih.gov/pubmed/33596089
http://dx.doi.org/10.1091/mbc.E20-12-0775

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