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Predicting cell health phenotypes using image-based morphology profiling

Genetic and chemical perturbations impact diverse cellular phenotypes, including multiple indicators of cell health. These readouts reveal toxicity and antitumorigenic effects relevant to drug discovery and personalized medicine. We developed two customized microscopy assays, one using four targeted...

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Detalles Bibliográficos
Autores principales: Way, Gregory P., Kost-Alimova, Maria, Shibue, Tsukasa, Harrington, William F., Gill, Stanley, Piccioni, Federica, Becker, Tim, Shafqat-Abbasi, Hamdah, Hahn, William C., Carpenter, Anne E., Vazquez, Francisca, Singh, Shantanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108524/
https://www.ncbi.nlm.nih.gov/pubmed/33534641
http://dx.doi.org/10.1091/mbc.E20-12-0784