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Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription

Nucleoli are dynamic nuclear condensates in eukaryotic cells that originate through ribosome biogenesis at loci that harbor the ribosomal DNA. These loci are known as nucleolar organizer regions (NORs), and there are 10 in a human diploid genome. While there are 10 NORs, however, the number of nucle...

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Detalles Bibliográficos
Autores principales: Ogawa, Lisa M., Buhagiar, Amber F., Abriola, Laura, Leland, Bryan A., Surovtseva, Yulia V., Baserga, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108525/
https://www.ncbi.nlm.nih.gov/pubmed/33689394
http://dx.doi.org/10.1091/mbc.E20-10-0670