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Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription
Nucleoli are dynamic nuclear condensates in eukaryotic cells that originate through ribosome biogenesis at loci that harbor the ribosomal DNA. These loci are known as nucleolar organizer regions (NORs), and there are 10 in a human diploid genome. While there are 10 NORs, however, the number of nucle...
Autores principales: | Ogawa, Lisa M., Buhagiar, Amber F., Abriola, Laura, Leland, Bryan A., Surovtseva, Yulia V., Baserga, Susan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108525/ https://www.ncbi.nlm.nih.gov/pubmed/33689394 http://dx.doi.org/10.1091/mbc.E20-10-0670 |
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