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Superresolution light microscopy of the Drosophila histone locus body reveals a core–shell organization associated with expression of replication–dependent histone genes

The histone locus body (HLB) is an evolutionarily conserved nuclear body that regulates the transcription and processing of replication-dependent (RD) histone mRNAs, which are the only eukaryotic mRNAs lacking a poly-A tail. Many nuclear bodies contain distinct domains, but how internal organization...

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Detalles Bibliográficos
Autores principales: Kemp, James P., Yang, Xiao-Cui, Dominski, Zbigniew, Marzluff, William F., Duronio, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108526/
https://www.ncbi.nlm.nih.gov/pubmed/33788585
http://dx.doi.org/10.1091/mbc.E20-10-0645