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Computational modeling of chromosome re-replication in mutant strains of fission yeast

Typically cells replicate their genome only once per division cycle, but under some circumstances, both natural and unnatural, cells synthesize an overabundance of DNA, either in a disorganized manner (“overreplication”) or by a systematic doubling of chromosome number (“endoreplication”). These var...

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Detalles Bibliográficos
Autores principales: Novák, Béla, Tyson, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108527/
https://www.ncbi.nlm.nih.gov/pubmed/33534609
http://dx.doi.org/10.1091/mbc.E20-09-0610