Molecular mechanisms underlying cellular effects of human MEK1 mutations

Terminal regions of Drosophila embryos are patterned by signaling through ERK, which is genetically deregulated in multiple human diseases. Quantitative studies of terminal patterning have been recently used to investigate gain-of-function variants of human MEK1, encoding the MEK kinase that directl...

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Detalles Bibliográficos
Autores principales: Marmion, Robert A., Yang, Liu, Goyal, Yogesh, Jindal, Granton A., Wetzel, Joshua L., Singh, Mona, Schüpbach, Trudi, Shvartsman, Stanislav Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108529/
https://www.ncbi.nlm.nih.gov/pubmed/33476180
http://dx.doi.org/10.1091/mbc.E20-10-0625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108529/
https://www.ncbi.nlm.nih.gov/pubmed/33476180
http://dx.doi.org/10.1091/mbc.E20-10-0625

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