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A quantitative and semiautomated method for determining misaligned and lagging chromosomes during mitosis

Accurate chromosome alignment at metaphase facilitates the equal segregation of sister chromatids to each of the nascent daughter cells. Lack of proper metaphase alignment is an indicator of defective chromosome congression and aberrant kinetochore–microtubule attachments which in turn promotes chro...

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Detalles Bibliográficos
Autores principales: Gama Braga, Luciano, Prifti, Diogjena Katerina, Garand, Chantal, Saini, Pawan Kumar, Elowe, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108530/
https://www.ncbi.nlm.nih.gov/pubmed/33085580
http://dx.doi.org/10.1091/mbc.E20-09-0585