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The regulation of immune checkpoints by the hypoxic tumor microenvironment

The tumor microenvironment (TME) influences the occurrence and progression of tumors, and hypoxia is an important characteristic of the TME. The expression of programmed death 1 (PD1)/programmed death-ligand 1 (PDL1), cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), and other immune checkpoints...

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Detalles Bibliográficos
Autores principales: Hu, Min, Li, Yongfu, Lu, Yuting, Wang, Miao, Li, Yingrui, Wang, Chaoying, Li, Qin, Zhao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109006/
https://www.ncbi.nlm.nih.gov/pubmed/34012727
http://dx.doi.org/10.7717/peerj.11306