Dexmedetomidine Protects Against Septic Liver Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT1 Signaling Pathway

Background: Liver injury is one of the serious complications of sepsis. Previous studies suggested that dexmedetomidine (DEX) could alleviate cecal ligation and puncture (CLP)-induced liver injury. However, it is unclear whether the protective effect of DEX on sepsis-induced liver injury is related...

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Detalles Bibliográficos
Autores principales: Yu, Qing, Zou, Liying, Yuan, Xiu, Fang, Fang, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109052/
https://www.ncbi.nlm.nih.gov/pubmed/33981237
http://dx.doi.org/10.3389/fphar.2021.658677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109052/
https://www.ncbi.nlm.nih.gov/pubmed/33981237
http://dx.doi.org/10.3389/fphar.2021.658677

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