Anti-oncogenic effects of SOX2 silencing on hepatocellular carcinoma achieved by upregulating miR-222-5p-dependent CYLD via the long noncoding RNA CCAT1

In this study, we determined the involvement of SOX2 and its downstream signaling molecules in hepatocellular carcinoma (HCC) progression. We carried out lentiviral transfection in HepG2 cells to determine the roles of SOX2, CCAT1, EGFR, miR-222-5p, and CYLD in HepG2 cells. We first determined the i...

Descripción completa

Detalles Bibliográficos
Autores principales: Pu, Jian, Wu, Xianjian, Wu, Yi, Shao, Zesheng, Luo, Chunying, Tang, Qianli, Wang, Jianchu, Wei, Huamei, Lu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109057/
https://www.ncbi.nlm.nih.gov/pubmed/33952719
http://dx.doi.org/10.18632/aging.103797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109057/
https://www.ncbi.nlm.nih.gov/pubmed/33952719
http://dx.doi.org/10.18632/aging.103797

Ejemplares similares