COX-2 promotes the osteogenic potential of BMP9 through TGF-β1/p38 signaling in mesenchymal stem cells

This study investigated the effects of transforming growth factor-β1 (TGF-β1) and cyclooxygenase-2 (COX-2) on bone morphogenetic protein 9 (BMP9) in mesenchymal stem cells (MSCs). We found that BMP9 increased mRNA levels of TGF-β1 and COX-2 in C3H10T1/2 cells. BMP9-induced osteogenic markers were en...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Yan, Li, Ling, Zhu, Jia-Hui, Li, Pei-Pei, Deng, Yi-Xuan, Luo, Hong-Hong, Yang, Yuan-Yuan, He, Bai-Cheng, Su, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109063/
https://www.ncbi.nlm.nih.gov/pubmed/33833129
http://dx.doi.org/10.18632/aging.202825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109063/
https://www.ncbi.nlm.nih.gov/pubmed/33833129
http://dx.doi.org/10.18632/aging.202825

Ejemplares similares