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Translational control of gene expression by eIF2 modulates proteostasis and extends lifespan

Although the stress response in eukaryotes depends on early events triggered in cells by environmental insults, long-term processes such as aging are also affected. The loss of cellular proteostasis greatly impacts aging, which is regulated by the balancing of protein synthesis and degradation syste...

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Detalles Bibliográficos
Autores principales: Jiménez-Saucedo, Tamara, Berlanga, Juan José, Rodríguez-Gabriel, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109070/
https://www.ncbi.nlm.nih.gov/pubmed/33901016
http://dx.doi.org/10.18632/aging.203018