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Two reactive behaviors of chondrocytes in an IL-1β-induced inflammatory environment revealed by the single-cell RNA sequencing

Objective: To investigate the heterogeneous responses of in vitro expanded chondrocytes, which were cultured in an interleukin (IL)-1β -induced inflammatory environment. Method: Human articular chondrocytes were expanded, in vitro, for 13 days and treated with IL-1β for 0, 24, and 48 h. Cells were c...

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Detalles Bibliográficos
Autores principales: Gao, Chenghao, Pu, Hongxu, Zhou, Qian, Tao, Tenghui, Liu, Hui, Sun, Xuying, He, Ximiao, Xiao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109072/
https://www.ncbi.nlm.nih.gov/pubmed/33879632
http://dx.doi.org/10.18632/aging.202857