Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1

Backgrounds: A major side effect of statin, a widely used drug to treat hyperlipidemia, is skeletal myopathy through cell apoptosis. The aim of this study is to investigate the roles of microRNA in statin-induced injury. Methods: Apolipoprotein E knockout (ApoE-/-) mice were administered with simvas...

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Detalles Bibliográficos
Autores principales: Fu, Chang-Ning, Song, Jia-Wen, Song, Zhi-Peng, Wang, Qian-Wen, Bai, Wen-Wu, Guo, Tao, Li, Peng, Liu, Chao, Wang, Shuang-Xi, Dong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109097/
https://www.ncbi.nlm.nih.gov/pubmed/33864447
http://dx.doi.org/10.18632/aging.202839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109097/
https://www.ncbi.nlm.nih.gov/pubmed/33864447
http://dx.doi.org/10.18632/aging.202839

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