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Excessive expression of miR-1a by statin causes skeletal injury through targeting mitogen-activated protein kinase kinase kinase 1
Backgrounds: A major side effect of statin, a widely used drug to treat hyperlipidemia, is skeletal myopathy through cell apoptosis. The aim of this study is to investigate the roles of microRNA in statin-induced injury. Methods: Apolipoprotein E knockout (ApoE-/-) mice were administered with simvas...
Autores principales: | Fu, Chang-Ning, Song, Jia-Wen, Song, Zhi-Peng, Wang, Qian-Wen, Bai, Wen-Wu, Guo, Tao, Li, Peng, Liu, Chao, Wang, Shuang-Xi, Dong, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109097/ https://www.ncbi.nlm.nih.gov/pubmed/33864447 http://dx.doi.org/10.18632/aging.202839 |
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