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Activation of GPR30 with G1 inhibits oscillatory shear stress-induced adhesion of THP-1 monocytes to HAECs by increasing KLF2

Atherosclerosis is a chronic inflammatory disease known to be mediated by numerous factors, among which endothelial dysfunction plays a critical role. Oscillatory shear stress induces endothelial cells to lose their anti-atherosclerotic properties and downregulates the expression of the innate prote...

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Detalles Bibliográficos
Autores principales: Chen, Chi, Chen, Jingyan, Tao, Xuefei, Fu, Minghuan, Cheng, Biao, Chen, Xiaohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109116/
https://www.ncbi.nlm.nih.gov/pubmed/33875621
http://dx.doi.org/10.18632/aging.202897