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Accelerating SARS-CoV-2 low frequency variant calling on ultra deep sequencing datasets

With recent advances in sequencing technology it has become affordable and practical to sequence genomes to very high depth-of-coverage, allowing researchers to discover low-frequency variants in the genome. However, due to the errors in sequencing it is an active area of research to develop algorit...

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Detalles Bibliográficos
Autores principales: Kille, Bryce, Liu, Yunxi, Sapoval, Nicolae, Nute, Michael, Rauchwerger, Lawrence, Amato, Nancy, Treangen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109184/
https://www.ncbi.nlm.nih.gov/pubmed/33972927