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Fit-for-purpose quantitative liquid biopsy based droplet digital PCR assay development for detection of programmed cell death ligand-1 (PD-L1) RNA expression in PAXgene blood samples

Development of a clinically applicable liquid biopsy-based test for PD-L1 mRNA expression would be beneficial in providing complementary evidence to current immunohistochemistry assays. Hence, we report the development of a fit-for-purpose assay for detection of blood PD-L1 mRNA expression using dro...

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Detalles Bibliográficos
Autores principales: O’Rourke, Dennis, Wang, Danyi, Sanchez-Garcia, Jorge F., Cusano, Maria Perella, Miller, Waldemar, Cai, Ti, Scheuenpflug, Juergen, Feng, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109819/
https://www.ncbi.nlm.nih.gov/pubmed/33970922
http://dx.doi.org/10.1371/journal.pone.0250849