ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection

Histones are rapidly loaded on the HSV genome upon entry into the nucleus of human fibroblasts, but the effects of histone loading on viral replication have not been fully defined. We showed recently that ATRX is dispensable for de novo deposition of H3 to HSV genomes after nuclear entry but restric...

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Detalles Bibliográficos
Autores principales: Cabral, Joseph M., Cushman, Camille H., Sodroski, Catherine N., Knipe, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109836/
https://www.ncbi.nlm.nih.gov/pubmed/33909709
http://dx.doi.org/10.1371/journal.ppat.1009567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109836/
https://www.ncbi.nlm.nih.gov/pubmed/33909709
http://dx.doi.org/10.1371/journal.ppat.1009567

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