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ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection
Histones are rapidly loaded on the HSV genome upon entry into the nucleus of human fibroblasts, but the effects of histone loading on viral replication have not been fully defined. We showed recently that ATRX is dispensable for de novo deposition of H3 to HSV genomes after nuclear entry but restric...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109836/ https://www.ncbi.nlm.nih.gov/pubmed/33909709 http://dx.doi.org/10.1371/journal.ppat.1009567 |