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Severe Bradycardia Increases the Incidence and Severity of Torsade de Pointes Arrhythmias by Augmenting Preexistent Spatial Dispersion of Repolarization in the CAVB Dog Model

INTRODUCTION: Torsade de pointes arrhythmias (TdP) in the chronic atrioventricular block (CAVB) dog model result from proarrhythmic factors, which trigger TdP and/or reinforce the arrhythmic substrate. This study investigated electrophysiological and arrhythmogenic consequences of severe bradycardia...

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Detalles Bibliográficos
Autores principales: van Weperen, Valerie Y. H., Dunnink, Albert, Bossu, Alexandre, Beekman, Jet D. M., Meijborg, Veronique M. F., de Bakker, Jacques M. T., Coronel, Ruben, Varkevisser, Rosanne, van der Heyden, Marcel A. G., Vos, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110054/
https://www.ncbi.nlm.nih.gov/pubmed/33981248
http://dx.doi.org/10.3389/fphys.2021.642083