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The Predominant Prognostic Significance of NOTCH1 Mutation Defined by Emulsion PCR in Chronic Lymphocytic Leukemia

PURPOSE: NOTCH1(mut) represents a new prognostic marker in chronic lymphocytic leukaemia (CLL). The low sensitivity of the current methods may increase the risk of false-negative results, particularly in patients with low NOTCH1(mut) allelic burden. This study compared two methods of the NOTCH1(mut)...

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Detalles Bibliográficos
Autores principales: Skórka, Katarzyna, Chojnacki, Michał, Masternak, Marta, Karczmarczyk, Agnieszka, Subocz, Edyta, Wawrzyniak, Ewa, Giannopoulos, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110254/
https://www.ncbi.nlm.nih.gov/pubmed/33986614
http://dx.doi.org/10.2147/CMAR.S302245