Laboratory Verification of a BRCA1 and BRCA2 Massively Parallel Sequencing Assay from Wet Bench to Bioinformatics for Germline DNA Analysis

Introduction  A robust genetic test for BRCA1 and BRCA2 genes is necessary for the diagnosis, prognosis, and treatment of patients with hereditary breast and ovarian cancer. We evaluated a commercial amplicon-based massively parallel sequencing (MPS) assay, BRCA MASTR Plus on the MiSeq platform, for...

Descripción completa

Detalles Bibliográficos
Autores principales: Poon, Kok-Siong, Chiu, Lily, Tan, Karen Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110340/
https://www.ncbi.nlm.nih.gov/pubmed/33987625
http://dx.doi.org/10.1055/s-0041-1726338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110340/
https://www.ncbi.nlm.nih.gov/pubmed/33987625
http://dx.doi.org/10.1055/s-0041-1726338

Ejemplares similares