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2b or Not 2b: How Opposing FGF Receptor Splice Variants Are Blocking Progress in Precision Oncology

More than ten thousand peer-reviewed studies have assessed the role of fibroblast growth factors (FGFs) and their receptors (FGFRs) in cancer, but few patients have yet benefited from drugs targeting this molecular family. Strategizing how best to use FGFR-targeted drugs is complicated by multiple v...

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Detalles Bibliográficos
Autores principales: Epstein, Richard J., Tian, Li Jun, Gu, Yan Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110382/
https://www.ncbi.nlm.nih.gov/pubmed/34007277
http://dx.doi.org/10.1155/2021/9955456