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Glaucocalyxin A Attenuates Allergic Responses by Inhibiting Mast Cell Degranulation through p38MAPK/NrF2/HO-1 and HMGB1/TLR4/NF-κB Signaling Pathways

Glaucocalyxin A (GLA) has various pharmacological effects like antioxidation, immune regulation, and antiatherosclerosis. Here, in this study, the effect and mechanism of GLA on mast cell degranulation were studied. The results of the anti-DNP IgE-mediated passive cutaneous anaphylaxis (PCA) showed...

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Detalles Bibliográficos
Autores principales: Piao, Yihua, Jiang, Jingzhi, Wang, Zhiguang, Wang, Chongyang, Jin, Shan, Li, Li, Li, Liangchang, Piao, Hongmei, Jin, Zhehu, Zhu, Lianhua, Yan, Guanghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110394/
https://www.ncbi.nlm.nih.gov/pubmed/34007295
http://dx.doi.org/10.1155/2021/6644751