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Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes

Chromatin compartmentalization reflects biological activity. However, inference of chromatin sub-compartments and compartment domains from chromosome conformation capture (Hi-C) experiments is limited by data resolution. As a result, these have been characterized only in a few cell types and systema...

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Detalles Bibliográficos
Autores principales: Liu, Yuanlong, Nanni, Luca, Sungalee, Stephanie, Zufferey, Marie, Tavernari, Daniele, Mina, Marco, Ceri, Stefano, Oricchio, Elisa, Ciriello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110550/
https://www.ncbi.nlm.nih.gov/pubmed/33972523
http://dx.doi.org/10.1038/s41467-021-22666-3