Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Synaptic disturbances in excitatory to inhibitory (E/I) balance in forebrain circuits are thought to contribute to the progression of Alzheimer’s disease (AD) and dementia, although direct evidence for such imbalance in humans is lacking. We assessed anatomical and electrophysiological synaptic E/I...

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Detalles Bibliográficos
Autores principales: Lauterborn, Julie C., Scaduto, Pietro, Cox, Conor D., Schulmann, Anton, Lynch, Gary, Gall, Christine M., Keene, C. Dirk, Limon, Agenor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110554/
https://www.ncbi.nlm.nih.gov/pubmed/33972518
http://dx.doi.org/10.1038/s41467-021-22742-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110554/
https://www.ncbi.nlm.nih.gov/pubmed/33972518
http://dx.doi.org/10.1038/s41467-021-22742-8

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