High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice

Repeated head impact exposure can cause memory and behavioral impairments. Here, we report that exposure to non-damaging, but high frequency, head impacts can alter brain function in mice through synaptic adaptation. High frequency head impact mice develop chronic cognitive impairments in the absenc...

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Detalles Bibliográficos
Autores principales: Sloley, Stephanie S., Main, Bevan S., Winston, Charisse N., Harvey, Alex C., Kaganovich, Alice, Korthas, Holly T., Caccavano, Adam P., Zapple, David N., Wu, Jian-young, Partridge, John G., Cookson, Mark R., Vicini, Stefano, Burns, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110563/
https://www.ncbi.nlm.nih.gov/pubmed/33972519
http://dx.doi.org/10.1038/s41467-021-22744-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110563/
https://www.ncbi.nlm.nih.gov/pubmed/33972519
http://dx.doi.org/10.1038/s41467-021-22744-6

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