Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template

The RNA-dependent RNA polymerase of the severe acute respiratory syndrome coronavirus 2 is an important target in current drug development efforts for the treatment of coronavirus disease 2019. Molnupiravir is a broad-spectrum antiviral that is an orally bioavailable prodrug of the nucleoside analog...

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Detalles Bibliográficos
Autores principales: Gordon, Calvin J., Tchesnokov, Egor P., Schinazi, Raymond F., Götte, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110631/
https://www.ncbi.nlm.nih.gov/pubmed/33989635
http://dx.doi.org/10.1016/j.jbc.2021.100770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110631/
https://www.ncbi.nlm.nih.gov/pubmed/33989635
http://dx.doi.org/10.1016/j.jbc.2021.100770

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