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Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway
Excess fructose consumption contributes to development obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). Uric acid (UA), a metabolite of fructose metabolism, may have a direct role in development of NAFLD, with unclear mechanism. This study aimed to evaluate role of fructose...
Autores principales: | Cho, In-Jin, Oh, Da-Hee, Yoo, Jin, Hwang, You-Cheol, Ahn, Kyu Jeung, Chung, Ho-Yeon, Jeong, Soung Won, Moon, Ju-Young, Lee, Sang-Ho, Lim, Sung-Jig, Jeong, In-Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110790/ https://www.ncbi.nlm.nih.gov/pubmed/33972568 http://dx.doi.org/10.1038/s41598-021-88872-7 |
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