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Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

Disturbed shear stress is thought to be the driving factor of neointimal hyperplasia in blood vessels and grafts, for example in hemodialysis conduits. Despite the common occurrence of neointimal hyperplasia, however, the mechanistic role of shear stress is unclear. This is especially problematic in...

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Detalles Bibliográficos
Autores principales: van Haaften, Eline E., Quicken, Sjeng, Huberts, Wouter, Bouten, Carlijn V. C., Kurniawan, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110791/
https://www.ncbi.nlm.nih.gov/pubmed/33972658
http://dx.doi.org/10.1038/s42003-021-02065-6