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Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis

Epithelial-to-mesenchymal transition (EMT) is the most commonly cited mechanism for cancer metastasis, but it is difficult to distinguish from profiles of normal stromal cells in the tumour microenvironment. In this study we use published single cell RNA-seq data to directly compare mesenchymal sign...

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Detalles Bibliográficos
Autores principales: Tyler, Michael, Tirosh, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110844/
https://www.ncbi.nlm.nih.gov/pubmed/33972543
http://dx.doi.org/10.1038/s41467-021-22800-1