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Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis
Epithelial-to-mesenchymal transition (EMT) is the most commonly cited mechanism for cancer metastasis, but it is difficult to distinguish from profiles of normal stromal cells in the tumour microenvironment. In this study we use published single cell RNA-seq data to directly compare mesenchymal sign...
Autores principales: | Tyler, Michael, Tirosh, Itay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110844/ https://www.ncbi.nlm.nih.gov/pubmed/33972543 http://dx.doi.org/10.1038/s41467-021-22800-1 |
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