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Large Acid-Evoked Currents, Mediated by ASIC1a, Accompany Differentiation in Human Dopaminergic Neurons

Acid-sensing ion channels (ASICs) are proton-gated Na(+) channels. They contribute to synaptic transmission, neuronal differentiation and neurodegeneration. ASICs have been mainly characterized in neurons from mice or rats and our knowledge of their properties in human neurons is scarce. Here, we fu...

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Detalles Bibliográficos
Autores principales: Neuhof, Andreas, Tian, Yuemin, Reska, Anna, Falkenburger, Björn H., Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110905/
https://www.ncbi.nlm.nih.gov/pubmed/33986647
http://dx.doi.org/10.3389/fncel.2021.668008